Searchable abstracts of presentations at key conferences in endocrinology

ea0035p1131 | Thyroid Cancer | ECE2014

The role of the transcription factor: Prospero homeobox 1: in the biology of differentiated thyroid cancer

Rudzinska Magdalena , Gawel Damian , Karpinska Kamila , Kierdrowski Miroslaw , Stepien Tomasz , Marchlewska Magdalena , Domek Hanna , Czarnocka Barbara

One of the pathways of DTC dissemination is the lymphatic system, however the molecular basis of this process is still unknown. One of the key regulators of lymphangiogesis is Prospero homeobox 1 (Prox1) specifically expressed in LEC and in some human cancers. The present study investigates the expression and function Prox1 in biology of differentiated cancer cells.Studies were performed in a series of thyroid cancer FTC and PTC cell lines. Protein and t...